Satellite Glial Cell Markers

In the drgs the cell bodies of these primary afferents are anatomically surrounded by satellite glial cells sgcs forming distinct functional units.

Satellite glial cell markers. Glial cell markers glial cells commonly called neuroglia or simply glia are non neuronal cells that provide support and nutrition maintain homeostasis form myelin and participate in signal transmission in the nervous system in. The most specific markers of astrocytes are gfap and s100β. Current topics and past controversies. Garden ga and campbell bm 2016 glial biomarkers in human central nervous system disease.

Here we developed the cellmarker databases aiming to provide a comprehensive and accurate resource of cell markers for various cell types in tissues of human and mouse. Overview for cellmarker by manually curating over 100 000 published papers 4 124 entries including the cell marker information tissue type cell type cancer information and source were recorded. From studies on rats and mice researchers have found that satellite glial cells express many neurotransmitter receptors such as muscarinic acetylcholine and erythropoietin receptors. Glutamine synthetase glial fibrillary acidic protein and s100β.

In a healthy nervous system astrocytes play essential roles in development regulation of blood flow by supporting endothelial cells in the blood brain barrier synaptic transmission and function and energy and metabolism by providing nutrients to neurons and synthesizing certain neurotransmitters. Ginhoux f and prinz m 2015 origin of microglia. Ginhoux f and prinz m 2015 origin of microglia. The p75ntr cells were also positive for the pan glial cell markers s100 nestin and sox10 but negative for fibroblast and macrophage markers.

Current topics and past controversies. In order to differentiate between sgcs and other glial cells researchers have used markers to identify which proteins are found in different cells. Garden ga and campbell bm 2016 glial biomarkers in human central nervous system disease. After subculture cells were identified by immunofluorescence labeling for three satellite glial cell specific markers.